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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2252279Generated: October 26, 2026

tert-Butyl piperazine-1-carboxylate → tert-Butyl 4-[5-chloro-1-(4-chlorophenyl)-6-oxo-1,6-dihydro-4-pyridazinyl]-1-piperazine carboxylate

https://huagongshe.com/reaction/2252279

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl piperazine-1-carboxylateHCID 143452—
Reactant4,5-Dichloro-2-(4-chlorophenyl)-3(2H)-pyridazinoneHCID 779402—
Producttert-Butyl 4-[5-chloro-1-(4-chlorophenyl)-6-oxo-1,6-dihydro-4-pyridazinyl]-1-piperazine carboxylateHCID 58585184—

Reaction Steps

By general method 1 from 20.66 g (75 mmol) of 2-(4-chlorophenyl)-4,5-dichloropyridazin-3-one with 25.14 g (135 mmol) of Boc-piperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07320977B2
Source datasetuspto-grants-2008_01
ORD IDord-bd1cf704a1e743c0bfabb7300c9d38c0
Source noteuspto-grants-2008_01