Chloroacetic Acid → HCID 72980313, compound

HRID 2252343Notes

Reaction equation

[CH2:1]([Cl:5])[C:2]([OH:4])=[O:3].[C:6]1([CH:12]=[CH:13][C:14]2[CH:15]=[C:16]([OH:24])[C:17]([CH:21]([CH3:23])[CH3:22])=[C:18](O)[CH:19]=2)[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1>>[Cl:5][CH2:1][C:2]([O:4][C:18]1[CH:19]=[C:14]([CH:13]=[CH:12][C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH:15]=[C:16]([O:24][C:2](=[O:3])[CH2:1][Cl:5])[C:17]=1[CH:21]([CH3:23])[CH3:22])=[O:3]

Participants

Reactant 2

HCID 300Chloroacetic Acid

HCID 133191HCID 133191, compound

Product 1

HCID 72980313HCID 72980313, compoundYield 72%

Procedure

This material was synthesized from anhydrous chloroacetic and 5-(2-Phenylethenyl)-2-i-propyl-1,3-benzenediol obtained in example 11 in 72% yield by the same procedure as described in example 12. 1HNMR (CDCl3, ppm): δ 1.30 (d, J=7.0 Hz, 6H), 3.08 (hept, J=7.0 Hz, 1H), 4.39 (s, 4H), 6.96 (d, J=17 Hz, 1H), 7.14 (d, J=17 Hz, 1H) 7.17 (s, 2H), 7.2-7.5 (m, 5H).

Sources & evidence

ORD record: ord-c3dd3995a7ec4786bb0e00e843fe679c
Source dataset: uspto-grants-2008_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07321050B2

Reaction notes

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