1-Bromo-2,6-difluorobenzene → 1-(2,6-Difluorophenyl)-2-(3,5-dimethoxy-4-i-propylphenyl)ethene

HRID 2252358Notes

Reaction equation

HRID 2252358 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:14]=[CH2:15])[CH:6]=[C:7]([O:12][CH3:13])[C:8]=1[CH:9]([CH3:11])[CH3:10].Br[C:17]1[C:22]([F:23])=[CH:21][CH:20]=[CH:19][C:18]=1[F:24]>>[F:23][C:22]1[CH:21]=[CH:20][CH:19]=[C:18]([F:24])[C:17]=1[CH:15]=[CH:14][C:5]1[CH:6]=[C:7]([O:12][CH3:13])[C:8]([CH:9]([CH3:11])[CH3:10])=[C:3]([O:2][CH3:1])[CH:4]=1

Participants

3

Reactant 2

HCID 1235571-Bromo-2,6-difluorobenzeneHCID 69099819(3,5-Dimethoxy-4-i-propylphenyl)ethene

Product 1

HCID 690998911-(2,6-Difluorophenyl)-2-(3,5-dimethoxy-4-i-propylphenyl)ethene

Procedure

This compound was synthesized from (3,5-dimethoxy-4-i-propylphenyl)ethene and 1-bromo-2,6-diflurobenzene quantitatively in the same procedure as described in preparation of 31B. 1HNMR (CDCl3, ppm): δ 1.32 (d, J=7.1 Hz, 6H), 3.62 (qint, J=7.1 Hz, 1H), 3.90 (s, 6H), 6.73 (s, 2H), 6.8-7.2 (m, 4H), 7.41 (d, J=16.6 Hz, 1H).

Sources & evidence

ORD record
ord-3ec0179fa7be46ba95bfe73c843bd25b
Source dataset
uspto-grants-2008_01
Patent number
US07321050B2

Reaction notes

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