1-Bromo-2,4,6-trifluorobenzene → 1-(3,5-Dimethoxy-4-i-propylphenyl)-2-(2,4,6-trifluorophenyl)ethene

HRID 2252359Notes

Reaction equation

HRID 2252359 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:14]=[CH2:15])[CH:6]=[C:7]([O:12][CH3:13])[C:8]=1[CH:9]([CH3:11])[CH3:10].Br[C:17]1[C:22]([F:23])=[CH:21][C:20]([F:24])=[CH:19][C:18]=1[F:25]>>[CH3:13][O:12][C:7]1[CH:6]=[C:5]([CH:14]=[CH:15][C:21]2[C:22]([F:23])=[CH:17][C:18]([F:25])=[CH:19][C:20]=2[F:24])[CH:4]=[C:3]([O:2][CH3:1])[C:8]=1[CH:9]([CH3:11])[CH3:10]

Participants

3

Reactant 2

HCID 753981-Bromo-2,4,6-trifluorobenzeneHCID 69099819(3,5-Dimethoxy-4-i-propylphenyl)ethene

Product 1

HCID 690997671-(3,5-Dimethoxy-4-i-propylphenyl)-2-(2,4,6-trifluorophenyl)etheneYield 58%

Procedure

This compound was synthesized from (3,5-dimethoxy-4-i-propylphenyl)ethene and 1-bromo-2,4,6-triflurobenzene in 58% yield in the same procedure as described in preparation of 31B. 1HNMR (CDCl3, ppm): δ 1.32 (d, J=7.0 Hz, 6H), 3.62 (qint, J=7.1 Hz, 1H), 3.89 (s, 6H), 6.73 (s, 2H), 6.79-7.55 (m, 4H).

Sources & evidence

ORD record
ord-d2def532cdde4cb6b4034d8c5402a6cf
Source dataset
uspto-grants-2008_01
Patent number
US07321050B2

Reaction notes

Loading…