HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrazole, 3-amino-4-cyano-5-ethyl- → 2-Ethyl-7-phenylpyrazolo[1,5-a]pyrimidine-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrazole, 3-amino-4-cyano-5-ethyl- | HCID 114021 | — |
| Reactant | 3-(Dimethylamino)-1-phenyl-2-propen-1-one | HCID 353460 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 2-Ethyl-7-phenylpyrazolo[1,5-a]pyrimidine-3-carbonitrile | HCID 23329865 | — |
Reaction Steps
A mixture of 0.71 g. of 3-dimethylaminoacrylophenone, 15 ml. of glacial acetic acid and 0.55 g. of 3-amino-5-ethylpyrazole-4-carbonitrile is refluxed for 16 hours and then evaporated. The residue is treated as described in Example 1, giving the desired product, m.p. 132°-134° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04236005 |
| Source dataset | uspto-grants-1980_11 |
| ORD ID | ord-c03202d10e164bc3992b5fcb05806c0a |
| Source note | uspto-grants-1980_11 |