HuagongsheHuagongshe Chemistry Print Report · For research reference only
Butyl iodide → HCID 69300386, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Butyl iodide | HCID 10962 | — |
| Reactant | HCID 69300313 | HCID 69300313 | — |
| Product | HCID 69300386 | HCID 69300386 | 62% |
Reaction Steps
In a manner similar to the method described in Example 36-2, using 1-(3-benzyloxy-17-cyclopropylmethyl-4,5α-epoxy-14-hydroxy-morphinan-6α-yl)-pyrrolidin-2-one obtained in Example 36-1, and using iodobutane in place of iodoethane, 203 mg (yield: 62%) of the captioned compound was obtained as a diastereomer mixture.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07320984B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-e5f78b661a73472e978bc2a485f95b25 |
| Source note | uspto-grants-2008_01 |