HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetyl chloride → N-{4-Bromo-2-[1-(2-furyl)-1-hydroxyethyl]phenyl}-2-chloroacetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetyl chloride | HCID 6577 | — |
| Reactant | 1-(2-Amino-5-bromophenyl)-1-(2-furyl)ethanol | HCID 68865135 | — |
| Product | N-{4-Bromo-2-[1-(2-furyl)-1-hydroxyethyl]phenyl}-2-chloroacetamide | HCID 68864165 | — |
Reaction Steps
Prepared from 1-(2-amino-5-bromophenyl)-1-(2-furyl)ethanol and chloroacetyl chloride generally according to the procedure described in example 1. 1H-NMR (DMSO-d6) δ 10.84 (s, 1H), 8.07 (d, J=8.76 Hz. 1H), 7.57 (bs, 1H), 7.50 (dd, J=2.33, 8,76 Hz, 1H), 7.12 (s, 1H), 7.09 (d, J=2.31 Hz, 1H), 6.46-6.42 (m, 2H), 4.35 (d, J=1.69 Hz, 2H), 1.85 (s, 3H); MS (ES) m/z 356/358 ([M−H]−, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07323455B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-ff4a7e3e23cc4db6957d6bd7bb5ddd46 |
| Source note | uspto-grants-2008_01 |