(3-Cyano-5-fluorophenyl)boronic acid → HCID 11315741, compound

Participants

Reaction Steps

Prepared from 7-bromo-5-isopropyl-5-thien-2-yl-1,5-dihydro-4,1-benzoxazepin-2(3H)-one and 3-cyano-5-fluorobenzeneboronic acid using the coupling procedure described in example 1. 1H-NMR (DMSO-d6) δ 10.07 (s, 1H), 8.03 (s, 1H), 7.90 (m, 1H), 7.84 (m, 1H), 7.77 (m, 2H), 7.51 (dd, J=5.0, 1.2 Hz, 1H), 7.24 (d, J=8.5 Hz, 1H), 7.04 (m, 2H), 4.20 (d, J=14.4 Hz, 1H), 3.96 (d, J=14.4 Hz, 1H), 2.90 (m, 1H), 0.92 (t, J=6.4 Hz, 6H); MS (ES) m/z 407 (M+H)+.

Provenance & Evidence