反应详情

A mixture of 0.01 mole of 3-amino-4-methylpyrazole and 0.01 mole of 3-dimethylamino-3'-(trifluoromethyl)acrylophenone in glacial acetic acid is refluxed for 6 hours. The solvent is removed and the residue dissolved in methylene chloride and passed through a column of hydrous magnesium silicate. Concentration of the eluent and addition of hexane gives the product of the example.

1. temperatureis refluxed for 6 hours
2. customThe solvent is removed
3. dissolutionthe residue dissolved in methylene chloride
4. additionConcentration of the eluent and addition of hexane
5. customgives the product of the example