Aniline → HCID 10149863, compound

HRID 2252660Notes

Reaction equation

HRID 2252660 reaction equation
NC1C=CC=CC=1.[C:8]1([CH:14]2[CH2:19][CH2:18][CH2:17][CH2:16][N:15]2[C:20]2[CH:25]=[CH:24][N:23]=[C:22]([NH:26][C:27]3[CH:28]=[C:29]([CH:32]=[CH:33][CH:34]=3)C#N)[N:21]=2)[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>>[C:27]1([NH:26][C:22]2[N:21]=[C:20]([N:15]3[CH2:16][CH2:17][CH2:18][CH2:19][CH:14]3[C:8]3[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=3)[CH:25]=[CH:24][N:23]=2)[CH:28]=[CH:29][CH:32]=[CH:33][CH:34]=1

Participants

3

Reactant 2

HCID 6115AnilineHCID 10172337HCID 10172337, compound

Product 1

HCID 10149863HCID 10149863, compoundYield 82%

Procedure

Intermediate 16, (0.20 g, 0.73 mmol) and aniline (0.08 g, 0.80 mmol) were reacted together following the procedure detailed for the compound of Example 6, which gave the title compound as a white solid (0.22 g, 82%).

Sources & evidence

ORD record
ord-98e94a898d5b4d8ea8d6025640f75752
Source dataset
uspto-grants-2008_01
Patent number
US07323464B2

Reaction notes

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