HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aluminium lithium hydride → 4-(alpha,alpha,alpha-Trifluoro-m-tolyl)imidazo[1,5-a]pyrimidine-8-methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | Ethyl 4-(alpha,alpha,alpha-trifluoro-m-tolyl)imidazo[1,5-a]pyrimidine-8-carboxylate | HCID 23329853 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 4-(alpha,alpha,alpha-Trifluoro-m-tolyl)imidazo[1,5-a]pyrimidine-8-methanol | HCID 23329858 | — |
Reaction Steps
A mixture of ethyl 4-(α,α,α-trifluoro-m-tolyl)imidazo[1,5-a]pyrimidine-8-carboxylate is reduced with lithium aluminum hydride in refluxing tetrahydrofuran to give the product of the example.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04236005 |
| Source dataset | uspto-grants-1980_11 |
| ORD ID | ord-e7ff86d0bc244390816dbbb445963e98 |
| Source note | uspto-grants-1980_11 |