反应详情

A mixture of the product from Step B of Example 4 (24 mg) in aqueous ammonia (30%, 10 mL) was heated in a stainless steel autoclave at 100° C. overnight, then cooled and evaporated. The residue was purified on a silica gel column with CH2Cl2/MeOH (10/1 and 5/1) as the eluent to afford the title compound (15 mg).

1. temperaturecooled
2. customevaporated
3. customThe residue was purified on a silica gel column with CH2Cl2/MeOH (10/1 and 5/1) as the eluent