HuagongsheHuagongshe Chemistry Print Report · For research reference only
(E)-1-(3,4-dimethoxyphenyl)-3-(dimethylamino)-2-propen-1-one → Ethyl 7-(3,4-dimethoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (E)-1-(3,4-dimethoxyphenyl)-3-(dimethylamino)-2-propen-1-one | HCID 1481361 | — |
| Reactant | HCID 178469928 | HCID 178469928 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | Ethyl 7-(3,4-dimethoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate | HCID 11393271 | — |
Reaction Steps
A mixture of 2.35 g. of 3-dimethylamino-3',4'-dimethoxyacrylophenone and ethyl 3-aminopyrazole-4-carboxylate in 25 ml. of glacial acetic acid is refluxed for 20 hours and worked up to give the product, m.p. 148°-149° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04236005 |
| Source dataset | uspto-grants-1980_11 |
| ORD ID | ord-67d4d76690ca4a62a23807e6570034df |
| Source note | uspto-grants-1980_11 |