m-Chloroperbenzoic acid → HCID 59645349, compound

Participants

Reaction Steps

To a solution of Compound 100 (1 eq) in CH2Cl2 was added MCPBA (1.2 eg) at room temperature, the resulting mixture was stirred for 2 hrs, evaporated and chromatography on silica gel to give desired compound as a white solid. 1H NMR (400 MHz, DMSO) δ 8.01 (2H, d, J=8.4 Hz), 7.88(2H, d, J=8.4 Hz), 7.34˜7.28 (2H, m), 6.97 (1H, d, J=9.2 Hz), 4.77(2H, s), 4.42 (1H, d, J=13.6 Hz), 4.27 (1H, d, J=13.6 Hz), 2.14 (3H, s), 2.09 (3H, s).

Provenance & Evidence