HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sec-Butylamine → 4-Sec-butylamino-6-chloro-2-methylsulfanyl-pyrimidine-5-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sec-Butylamine | HCID 24874 | — |
| Reactant | 4,6-Dichloro-2-(methylsulfanyl)pyrimidine-5-carbaldehyde | HCID 4614004 | — |
| Product | 4-Sec-butylamino-6-chloro-2-methylsulfanyl-pyrimidine-5-carbaldehyde | HCID 59639584 | — |
Reaction Steps
Prepared as described above in Example 2 starting from 4,6-dichloro-2-methylsulfanyl-pyrimidine-5-carbaldehyde and 2-butylamine to give the title compound 4-sec-butylamino-6-chloro-2-methylsulfanyl-pyrimidine-5-carbaldehyde. 1H-NMR: δ 0.87 (m, 3H), 1.18 (m, 3H), 1.20 (m, 2H), 2.51 (s, 3H), 4.24 (m, 1H), 9.12 (br s, 1H), 10.18 (s, 1H). LC MS (m/e)=260 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07323472B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-0a708e648ccc4e269b677918192040c4 |
| Source note | uspto-grants-2008_01 |