Benzene, 1-bromo-3-(trifluoromethyl)- → HCID 58689696, compound

HRID 2252978Notes

Reaction equation

HRID 2252978 reaction equation
Br[C:2]1[CH:3]=[C:4]([C:8]([F:11])([F:10])[F:9])[CH:5]=[CH:6][CH:7]=1.[CH2:12]([C@@H:14]1[O:16][CH2:15]1)[Cl:13]>>[Cl:13][CH2:12][C@H:14]([OH:16])[CH2:15][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([C:8]([F:11])([F:10])[F:9])[CH:3]=1

Participants

3

Reactant 2

HCID 9817Benzene, 1-bromo-3-(trifluoromethyl)-HCID 2734062(-)-Epichlorohydrin

Product 1

HCID 58689696HCID 58689696, compound

Procedure

(R)-1-chloro-3-(3-trifluoromethylphenyl)-2-propanol was prepared using the same procedure as described for example 2, intermediate (d), but using 3-bromobenzotrifluoride and (R)-epichlorohydrin.

Sources & evidence

ORD record
ord-aa58db7ee7be47c087433ec16d708d1d
Source dataset
uspto-grants-2008_01
Patent number
US07323466B2

Reaction notes

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