3-Bromobenzyl bromide → HCID 67073061, compound

HRID 2253020Notes

Reaction equation

HRID 2253020 reaction equation
C(N1CCO[C@H](CC2C=CC=C(CO)C=2)C1)(OC(C)(C)C)=O.[CH2:23]([N:30]1[CH2:35][CH2:34][O:33][CH2:32][C:31]1=[O:36])[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1.[Br:37][C:38]1[CH:39]=[C:40]([CH:43]=[CH:44][CH:45]=1)[CH2:41]Br>>[CH2:23]([N:30]1[CH2:35][CH2:34][O:33][CH:32]([CH2:41][C:40]2[CH:43]=[CH:44][CH:45]=[C:38]([Br:37])[CH:39]=2)[C:31]1=[O:36])[C:24]1[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=1

Participants

4

Reactant 3

HCID 699793-Bromobenzyl bromideHCID 122940874-Benzylmorpholin-3-oneHCID 67073062N-Boc-(R)-2-(3-(hydroxymethyl)benzyl)morpholine

Product 1

HCID 67073061HCID 67073061, compound

Procedure

N-Benzyl-2-(3-bromobenzyl)-morpholin-3-one was prepared as described for example 71, intermediate (b), but using 4-benzylmorpholine-3-one and 3-bromobenzyl bromide and was isolated as a pale yellow oil.

Workup

  1. customwas isolated as a pale yellow oil

Sources & evidence

ORD record
ord-26076c500bbb4981ad2e84f34b894803
Source dataset
uspto-grants-2008_01
Patent number
US07323466B2

Reaction notes

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