Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2253064Generated: October 31, 2026

Alanine methyl ester hydrochloride → (7-Isopropoxy-1-chloro-4-hydroxy-isoquinoline-3-carbonyl)-amino-propionic acid

https://huagongshe.com/reaction/2253064

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAlanine methyl ester hydrochlorideHCID 2733257—
Reactant1-Chloro-4-hydroxy-7-isopropoxy-isoquinoline-3-carboxylic acidHCID 53870439—
Product(7-Isopropoxy-1-chloro-4-hydroxy-isoquinoline-3-carbonyl)-amino-propionic acidHCID 86595459—

Reaction Steps

Analogously to Example A-56, 0.040 g of 7-isopropoxy-1-chloro-4-hydroxy-isoquinoline-3-carboxylic acid were allowed to react with 0.020 g of L-Alanine methyl ester hydrochloride to give, after hydrolysis of the intermediate ester, 0.047 g of a white solid: MS-(−)-ion, M−1=353.1 amu.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07323475B2
Source datasetuspto-grants-2008_01
ORD IDord-a1bd2d17e56b49ef81f148d266aeeb83
Source noteuspto-grants-2008_01