HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Trifluoromethyl)benzene-1-sulfonamide → N-{3-[4-(1,2-diphenyl-but-1-enyl)-phenyl]-acryloyl}-3-trifluoromethyl-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Trifluoromethyl)benzene-1-sulfonamide | HCID 244076 | — |
| Reactant | 3-[4-(Z)-(1,2-diphenylbut-1-enyl)phenyl]-acrylic acid | HCID 3036152 | — |
| Product | N-{3-[4-(1,2-diphenyl-but-1-enyl)-phenyl]-acryloyl}-3-trifluoromethyl-benzenesulfonamide | HCID 69781535 | — |
Reaction Steps
Prepared by coupling 1a and 3-(trifluoromethyl) benzenesulfonamide (Synlett, 1997, 375) in accordance with Procedure 1, Method B described hereinabove. Yield (35%); 1H NMR (d6-DMSO) δ 8.22-8.08 (m, 3H), 7.86 (t, J=7.7 Hz, 1H), 7.42-7.07 (m, 13H), 6.84 (d, J=8.0 Hz, 2H), 6.40 (d, J=15.7 Hz, 1H), 2.35 (q, J=7.3 Hz, 2H), 0.82 (t, J=7.3 Hz, 3H); APcI m/z: 562 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07323587B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-10e3b33fd56547bc84dd49b4d8600e6c |
| Source note | uspto-grants-2008_01 |