HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Trifluoromethyl)benzenesulfonamide → N-{3-[4-(1,2-diphenyl-but-1-enyl)-phenyl]-acryloyl}-4-trifluoromethyl-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Trifluoromethyl)benzenesulfonamide | HCID 70018 | — |
| Reactant | 3-[4-(Z)-(1,2-diphenylbut-1-enyl)phenyl]-acrylic acid | HCID 3036152 | — |
| Product | N-{3-[4-(1,2-diphenyl-but-1-enyl)-phenyl]-acryloyl}-4-trifluoromethyl-benzenesulfonamide | HCID 69780578 | — |
Reaction Steps
Prepared by coupling of 1a and 4-(trifluoromethyl)benzenesulfonamide (Synlett, 1997, 375) in accordance with Procedure 1, Method B described hereinabove. Yield (18%); 1H NMR (d6-DMSO) δ 12.46 (br s, 1H), 8.11 (d, J=8.5 Hz, 2H), 7.99 (d, J=8.5 Hz, 2H), 7.40-7.07 (m, 13H), 6.84 (d, J=8.1 Hz, 2H), 6.40 (d, J=15.7 Hz, 1H), 2.35 (q, J=7.3 Hz, 2H), 0.81 (t, J=7.3 Hz, 3H); APcI m/z: 562 (M+H+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07323587B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-1096a89b76ae47c48abbc7a4b431a848 |
| Source note | uspto-grants-2008_01 |