HRID2253467

反应详情

EQUATION

反应方程式

REACTANTS

反应物

$结构：CC/C(=C(\c1ccccc1)c1ccc(C=CC(=O)O)cc1)c1ccccc1$

HCID3036152

未命名化合物

HCID14763060

3-Methoxybenzene-1-sulfonamide

C7H9NO3S

PRODUCTS

生成物

结构：CCC(=C(c1ccccc1)c1ccc(C=CC(=O)NS(=O)(=O)c2cccc(OC)c2)cc1)c1ccccc1

HCID69780580

未命名化合物

PROCEDURE

实验过程

Prepared by coupling 1a and 3-methoxybenzenesulfonamide (Synlett, 1997, 375) in accordance with Procedure 1, Method B describe hereinabove. Yield (27%); 1H NMR (d6-DMSO) δ 12.18 (br s, 1H), 7.53-7.07 (m, 17H), 6.84 (d, J=8.0 Hz, 2H), 6.40 (d, J=15.7 Hz, 1H), 3.78 (s, 3H), 2.35 (q, J=7.4 Hz, 2H), 0.82 (t, J=7.4 Hz, 3H); APcI m/z: 522 (M−H−).

WORKUP

后处理

customPrepared
customYield (27%)

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-21f2f4dca4e548738f207d6cd907e106
来源数据集: uspto-grants-2008_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07323587B2
来源说明: uspto-grants-2008_01

反应 SMILES

[C:1]1(/[C:7](/[C:17]2[CH:22]=[CH:21][C:20]([CH:23]=[CH:24][C:25](O)=[O:26])=[CH:19][CH:18]=2)=[C:8](/[C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)\[CH2:9][CH3:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:28][O:29][C:30]1[CH:31]=[C:32]([S:36]([NH2:39])(=[O:38])=[O:37])[CH:33]=[CH:34][CH:35]=1>>[C:1]1([C:7]([C:17]2[CH:22]=[CH:21][C:20]([CH:23]=[CH:24][C:25]([NH:39][S:36]([C:32]3[CH:33]=[CH:34][CH:35]=[C:30]([O:29][CH3:28])[CH:31]=3)(=[O:38])=[O:37])=[O:26])=[CH:19][CH:18]=2)=[C:8]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH2:9][CH3:10])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1