HCID 15158302, compound → HCID 15034745, compound

Participants

Reaction Steps

A solution of 4.87 g of 1-(3-p-methoxyphenyloxazolidin-2-one-5-yl-methyl)-4-(3,4-methylenedioxyphenyl)pyridinium bromide [obtainable from 3-p-methoxyphenyl-5-bromomethyloxazolidin-2-one and 4-(3,4-methylenedioxyphenyl)pyridine] in 60 ml of acetic acid is hydrogenated over 1 g of 10% strength Pd/carbon at 20° and atmospheric pressure until the absorption of hydrogen has ceased. After filtration, evaporation and usual workup, 3-p-methoxyphenyl-5-[4-(3,4-methylenedioxyphenyl)piperidinomethyl]oxazolidin-2-one is obtained.

Provenance & Evidence