2-Amino-1-(3-chlorophenyl)ethan-1-ol → HCID 14368651, compound
Reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]([OH:11])[CH2:9][NH2:10])[CH:5]=[CH:6][CH:7]=1.[CH2:12]([C:16]1[CH:21]=[CH:20][C:19]([C:22]2[CH:27]=[CH:26][C:25]([O:28][CH3:29])=[CH:24][CH:23]=2)=[CH:18][CH:17]=1)[C:13]([CH3:15])=O>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]([OH:11])[CH2:9][NH:10][CH:13]([CH3:15])[CH2:12][C:16]2[CH:21]=[CH:20][C:19]([C:22]3[CH:27]=[CH:26][C:25]([O:28][CH3:29])=[CH:24][CH:23]=3)=[CH:18][CH:17]=2)[CH:5]=[CH:6][CH:7]=1Participants
3
Procedure
Yield: 20.1% of theory, Prepared from 2-(3-chloro-phenyl)-2-hydroxy-ethylamine and 4'-acetonyl-4-methoxy-biphenyl.
Sources & evidence
- ORD record
- ord-b11baa32b4c94c11aad9428c6dfae927
- Source dataset
- uspto-grants-1993_08
- Patent number
- US05232946
Reaction notes
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