Lithium tri-tert-butoxyaluminohydride → HCID 19746854, compound

Participants

Reaction Steps

A solution of 1.01 g (3.0 mmol) of the title compound of Example 7 and 2.5 g (10 mmol) of lithium tris-t-butoxyaluminum hydride in 250 mL of tetrahydrofuran under N2 was stirred overnight at room temperature. After dilution with ether the mixture was washed sequentially with saturated solutions of Na-K tartrate, NaCl, then dried and the solvents removed. The residue was dissolved in 100 mL of Skellysolve A, decolorized with activated charcoal, the mixture filtered and the filtrate evaporated. The residue was dried at 40°/3 mm to yield 0.92 g of a cloudy oil.

Provenance & Evidence