HCID 14050775, compound → HCID 19746693, compound

Participants

Reaction Steps

2-(5-Tert-butyloxycarbonylamino-1,2,4-thiadiazol-3-yl)-2-oxoacetic acid (1.49 g) was dissolved in methanol (60 ml), and to this solution a solution of diphenylmethyl (3,4-diacetoxyphenyl)-2-aminooxyacetate (2.45 g) in methanol (25 ml) was added dropwise. The mixture was stirred for 3 hrs. at the room temperature, and the solvent was evaporated to obtain (Z)-2-(5-tert-butyloxycarbonylamino-1,2,4-thiadiazol-3-yl)-2-[[(diphenylmethyloxycarbonyl)(3,4-diacetoxyphenyl)methoxy]imino]acetic acid (3.84 g).

Provenance & Evidence