HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → HCID 19743989, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | HCID 19743981 | HCID 19743981 | — |
| Reactant | 7-Acetyl-2H-1,4-benzothiazin-3(4H)-one | HCID 19744003 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 19743989 | HCID 19743989 | — |
Reaction Steps
Using the procedure described in Example 5 but replacing 6-(2-bromoethyl)benzothiazolinone by 7-(2-bromoethyl) 2,3-dihydro 3-oxo 1,4-benzothiazine (obtained using 7-acetyl 2,3-dihydro 3-oxo 1,4-benzothiazine (described in Ann. Chem. Rome, 1955, 45, 172) treated with bromine in methylene chloride to give 7-bromoacetyl 2,3-dihydro 3-oxo 1,4-benzothiazine, then by triethysilane in acidic medium to give 7-(2-bromoethyl)2,3-dihydro 3-oxo 1,4-benzothiazine, the product of the title is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05234924 |
| Source dataset | uspto-grants-1993_08 |
| ORD ID | ord-6c736c131f45466186e028aa455a9e99 |
| Source note | uspto-grants-1993_08 |