Ammonia → HCID 5152168, compound

HRID 2254052Notes

Reaction equation

HRID 2254052 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][N:9]2[C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=3[C:12](=O)[O:11]C2=O)=[CH:4][CH:3]=1.[NH3:21]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][NH:9][C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=2[C:12]([NH2:21])=[O:11])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 771877HCID 771877, compound

Product 1

HCID 5152168HCID 5152168, compound

Procedure

In 400 ml of concentrated aqueous ammonia, 14.4 g of 1-(4-chlorophenylmethyl)-2H-3,1-benzoxazine-2,4(1H)-dione were heated to 100° C. and stirred for 3 hours. After cooling, the crystals were collected by filtration, washed with water and dried. They were recrystallized from ethanol to obtain 8.6 g of title compound. m.p. 138°-139° C.

Workup

  1. temperatureAfter cooling
  2. filtrationthe crystals were collected by filtration
  3. washwashed with water
  4. customdried
  5. customThey were recrystallized from ethanol

Sources & evidence

ORD record
ord-e69a7a764ad94e20b7648b9bc3f04c37
Source dataset
uspto-grants-1993_08
Patent number
US05234928

Reaction notes

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