1,4-Dioxane → HCID 54005561, compound

Participants

Reaction Conditions

Reaction Steps

Into 10 ml of dioxane were dissolved 5.2 g of ethyl (2-((2,4-dichlorophenyl)methyl)amino-5-methoxybenzoyl)aminoacetate and 6.2 g of N,N'-carbonyldiimidazole, and the solution was heated to 140° to 150° C. After distilled off dioxane, the mixture was further heated for 15 minutes at 140° C. After cooling, ethanol was added and the crystalline substances were collected by filtration. They were recrystallized from ethanol to obtain 2,8 g of title compound. m.p. 167°-168° C.

Provenance & Evidence