HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2254069Generated: October 26, 2026
Imidazole → 1-[[3-[[3-(Hexadecyloxy)-2-methoxypropoxy]methyl]phenyl]methyl]-1H-imidazol
https://huagongshe.com/reaction/2254069
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | 1-(Bromomethyl)-3-[[3-(hexadecyloxy)-2-methoxypropoxy]methyl]benzene | HCID 19939557 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 1-[[3-[[3-(Hexadecyloxy)-2-methoxypropoxy]methyl]phenyl]methyl]-1H-imidazol | HCID 19939546 | 86.3% |
Reaction Steps
A mixture of 2.4 g of 1-(bromomethyl)-3-[[3-(hexadecyloxy)-2-methoxypropoxy]methyl]benzene, 2.54 g of imidazole and 30 ml of toluene was heated at 80° C. under argon in a pressure bottle for 4 hours and then evaporated. The residue was purified by chromatography, giving 2.02 g of the desired product as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05234918 |
|---|
| Source dataset | uspto-grants-1993_08 |
|---|
| ORD ID | ord-75131d552c074ec2bd045d43e1b7c9f6 |
|---|
| Source note | uspto-grants-1993_08 |
|---|
