HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → 3-(Bromomethyl)benzoic acid, 3-(hexadecyloxy)-2-methoxypropyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 1-O-hexadecyl-2-O-methylglycerol | HCID 1380 | — |
| Reactant | 3-(Bromomethyl)benzoyl chloride | HCID 14471076 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-(Bromomethyl)benzoic acid, 3-(hexadecyloxy)-2-methoxypropyl ester | HCID 57087588 | 78.3% |
Reaction Steps
A mixture of 8 g of 3-(hexadecyloxy)-2-methoxypropanol, 6.22 g of m-bromomethylbenzoyl chloride, 2.11 g of pyridine and 80 ml of tetrahydrofuran was stirred for 48 hours, then filtered and evaporated. The residue was purified by chromatography and crystallized giving 10 g of 3-(bromomethyl)benzoic acid, 3-(hexadecyloxy)-2-methoxypropyl ester as white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05234918 |
| Source dataset | uspto-grants-1993_08 |
| ORD ID | ord-bcd789485d8b4a1cad287d3a16199b2c |
| Source note | uspto-grants-1993_08 |