Methyl iodide → HCID 20080576, compound

HRID 2254166Notes

Reaction equation

HRID 2254166 reaction equation
[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([C:15]2([OH:23])[CH2:20][CH2:19][O:18][C:17]([CH3:22])([CH3:21])[CH2:16]2)[CH:12]=[CH:13][CH:14]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:24]I>>[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([C:15]2([O:23][CH3:24])[CH2:20][CH2:19][O:18][C:17]([CH3:21])([CH3:22])[CH2:16]2)[CH:12]=[CH:13][CH:14]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 200806534-(3-Benzyloxyphenyl)-4-hydroxy-2,2-dimethyltetrahydropyran

Product 1

HCID 20080576HCID 20080576, compoundYield 89%

Procedure

Using the procedure described in Example 3, 4-(3-benzyloxyphenyl)-4-hydroxy-2,2-dimethyltetrahydropyran (1.14 g) was reacted with methyl iodide (0.25 ml) to give 4-(3-benzyloxyphenyl)-4-methoxy-2,2-dimethyltetrahydropyran (1.06 g, 89%), as an oil.

Sources & evidence

ORD record
ord-b8780702461d4cae83a4c43e2176ed50
Source dataset
uspto-grants-1993_08
Patent number
US05234950

Reaction notes

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