HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromomethylnaphthalene → 4-Methoxy-2,6-dimethyl-4-[3-(naphth-2-ylmethoxy)phenyl]tetrahydropyran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromomethylnaphthalene | HCID 70320 | — |
| Reactant | 4-(3-Hydroxyphenyl)-4-methoxy-2,6-dimethyltetrahydropyran | HCID 20080618 | — |
| Product | 4-Methoxy-2,6-dimethyl-4-[3-(naphth-2-ylmethoxy)phenyl]tetrahydropyran | HCID 20080593 | 92% |
Reaction Steps
Using the procedure described in Example 5, 2-bromomethylnaphthalene (0.234 g) was reacted with 4-(3-hydroxyphenyl)-4-methoxy-2,6-dimethyltetrahydropyran (0.2 g, less polar isomer) to give 4-methoxy-2,6-dimethyl-4-[3-(naphth-2-ylmethoxy)phenyl]tetrahydropyran (0.29 g, 92%), m.p. 105°-107° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05234950 |
| Source dataset | uspto-grants-1993_08 |
| ORD ID | ord-8052f075ac5f4bef8f2584c4e57903f8 |
| Source note | uspto-grants-1993_08 |