2'-Hydroxy-3'-isopentyl-4',6'-bis(methoxymethoxy)acetophenone → 4-(Methoxymethoxy)benzaldehyde

HRID 2254259Notes

Reaction equation

HRID 2254259 reaction equation
O[C:2]1[C:7](CCC(C)C)=[C:6]([O:13][CH2:14][O:15][CH3:16])[CH:5]=[C:4](OCOC)[C:3]=1[C:21](=[O:23])C>CO>[CH3:16][O:15][CH2:14][O:13][C:6]1[CH:7]=[CH:2][C:3]([CH:21]=[O:23])=[CH:4][CH:5]=1

Participants

3

Reactant 1

HCID 160945312'-Hydroxy-3'-isopentyl-4',6'-bis(methoxymethoxy)acetophenone

Product 1

HCID 2500744-(Methoxymethoxy)benzaldehydeYield 100.3%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In 3 ml of methanol were dissolved 1.40 g of the 2'-hydroxy-4',6'-bis(methoxymethoxy)-3'-isopentylacetophenone obtained in Production Example 16 and 715 mg of the p-methoxymethoxybenzaldehyde obtained in Production Example 25, and a 50% ethanol solution of sodium hydroxide (4.0 g/8 ml) was added to the solution and the mixture was stirred at room temperature for 1 day to effect a reaction.

Sources & evidence

ORD record
ord-e771d82ef8f54c3ba79d34e1f6baf6cd
Source dataset
uspto-grants-1993_08
Patent number
US05234951

Reaction notes

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