HCID 53637082, compound → HCID 19744879, compound

HRID 2254268Notes

Reaction equation

HRID 2254268 reaction equation
[CH3:1][O:2][CH2:3][O:4][C:5]1[CH:28]=[C:27]([O:29][CH2:30][O:31][CH3:32])[CH:26]=[CH:25][C:6]=1[C:7](=[O:24])[CH:8]=[CH:9][C:10]1[CH:15]=[CH:14][C:13]([O:16][CH2:17][O:18][CH3:19])=[C:12]([O:20][CH2:21][O:22][CH3:23])[CH:11]=1>[Pd]>[CH3:1][O:2][CH2:3][O:4][C:5]1[CH:28]=[C:27]([O:29][CH2:30][O:31][CH3:32])[CH:26]=[CH:25][C:6]=1[C:7](=[O:24])[CH2:8][CH2:9][C:10]1[CH:15]=[CH:14][C:13]([O:16][CH2:17][O:18][CH3:19])=[C:12]([O:20][CH2:21][O:22][CH3:23])[CH:11]=1

Participants

3

Reactant 1

HCID 53637082HCID 53637082, compound

Product 1

HCID 19744879HCID 19744879, compoundYield 97.4%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

Catalytic reduction of 5.05 g of the 2',3,4,4'-tetrakis(methoxymethoxy)chalcone obtained as the intermediate in Specific Example 19 was carried out by using 1.76 g of 5% palladium/carbon according to customary procedures. After the reaction, the reaction liquid was filtered and the solvent was removed from the filtrate by distillation to obtain 4.94 g (yield=97.3%) of 1-[2,4-bis(methoxymethoxy)phenyl]-3-[3,4-bis(methoxymethoxy)phenyl] -1-propanone.

Workup

  1. customAfter the reaction
  2. customthe reaction liquid
  3. filtrationwas filtered
  4. customthe solvent was removed from the filtrate by distillation

Sources & evidence

ORD record
ord-223a117103f94423bc69f6280d421c24
Source dataset
uspto-grants-1993_08
Patent number
US05234951

Reaction notes

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