Methanol → HCID 13273039, compound

HRID 2254317Notes

Reaction equation

HRID 2254317 reaction equation
CO.[CH2:3]([O:10][C:11]1[CH:17]=[CH:16][C:14]([NH2:15])=[CH:13][CH:12]=1)[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[CH2:18]1[O:20][C@@H:19]1[CH2:21][OH:22]>C(O)C>[CH2:3]([O:10][C:11]1[CH:12]=[CH:13][C:14]([NH:15][CH2:18][CH:19]([OH:20])[CH2:21][OH:22])=[CH:16][CH:17]=1)[C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1

Participants

5

Reactant 3

HCID 887MethanolHCID 228604-BenzyloxyanilineHCID 5460455(+)-Glycidol

Product 1

HCID 13273039HCID 13273039, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The product is obtained with a 90% yield; m.p.: 102° C.; [α]D20 =+12,7° (c=1, CH3OH). This same product can be obtained by heating 4-benzyloxyaniline in ethanol in the presence of (R)-glycidol.

Workup

  1. customThe product is obtained with a 90% yield
  2. customThis same product can be obtained

Sources & evidence

ORD record
ord-7d00bf629d3a4487a63823da8f1459fd
Source dataset
uspto-grants-1993_08
Patent number
US05235063

Reaction notes

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