HRID2254370

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCOC(=O)CCc1cc(C(=O)c2cccc(C(=O)OCC)c2)ccc1O

HCID14739657

未命名化合物

HCID14739745

6-(4-Methoxyphenyl)hex-5-yn-1-ol

C13H16O2

PRODUCTS

生成物

结构：CCOC(=O)CCc1cc(C(=O)c2cccc(C(=O)OCC)c2)ccc1OCCCCC#Cc1ccc(OC)cc1

HCID14739789

未命名化合物

收率 55%

PROCEDURE

实验过程

Following the procedure of Example 92B, 0.38 g of 6-(4-methoxyphenyl)-5-hexynyl alcohol were converted to the mesyl ester and reacted with 0.69 g of 5-[3-(ethoxycarbonyl)benzoyl]-2-hydroxybenzenepropanoic acid ethyl ester to provide the title product in 55% yield as an oil.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-6699dd6d757f4381b8b5647983d47bd5
来源数据集: uspto-grants-1993_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05235064
来源说明: uspto-grants-1993_08

反应 SMILES

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]#[C:10][CH2:11][CH2:12][CH2:13][CH2:14][OH:15])=[CH:5][CH:4]=1.[CH2:16]([O:18][C:19](=[O:42])[CH2:20][CH2:21][C:22]1[CH:27]=[C:26]([C:28](=[O:40])[C:29]2[CH:34]=[CH:33][CH:32]=[C:31]([C:35]([O:37][CH2:38][CH3:39])=[O:36])[CH:30]=2)[CH:25]=[CH:24][C:23]=1O)[CH3:17]>>[CH2:16]([O:18][C:19](=[O:42])[CH2:20][CH2:21][C:22]1[CH:27]=[C:26]([C:28](=[O:40])[C:29]2[CH:34]=[CH:33][CH:32]=[C:31]([C:35]([O:37][CH2:38][CH3:39])=[O:36])[CH:30]=2)[CH:25]=[CH:24][C:23]=1[O:15][CH2:14][CH2:13][CH2:12][CH2:11][C:10]#[C:9][C:6]1[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=1)[CH3:17]