HRID2254371

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID85257

Methanesulfonate

CH3O3S-

结构：CCOC(=O)CCc1cc(C(=O)c2cccc(C(=O)OCC)c2)ccc1O

HCID14739657

未命名化合物

HCID14739746

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)CCc1cc(C(=O)c2cccc(C(=O)OCC)c2)ccc1OCCCCCCc1ccc(C(C)=O)cc1

HCID14739790

未命名化合物

收率 80.3%

PROCEDURE

实验过程

In a manner analogous to Example 92B, 2.85 g of 6-(4-acetylphenyl)hexanol were converted into its mesylate and reacted with 1.78 g of 5-[3-(ethoxycarbonyl)benzoyl]-2-hydroxybenzenepropanoic acid ethyl ester to provide 2.21 g of the desired title product as a pale yellow oil.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-d7c76b3e20de4e7996b2989fe5de35ba
来源数据集: uspto-grants-1993_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05235064
来源说明: uspto-grants-1993_08

反应 SMILES

[C:1]([C:4]1[CH:9]=[CH:8][C:7]([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][OH:16])=[CH:6][CH:5]=1)(=[O:3])[CH3:2].S([O-])(=O)(=O)C.[CH2:22]([O:24][C:25](=[O:48])[CH2:26][CH2:27][C:28]1[CH:33]=[C:32]([C:34](=[O:46])[C:35]2[CH:40]=[CH:39][CH:38]=[C:37]([C:41]([O:43][CH2:44][CH3:45])=[O:42])[CH:36]=2)[CH:31]=[CH:30][C:29]=1O)[CH3:23]>>[CH2:22]([O:24][C:25](=[O:48])[CH2:26][CH2:27][C:28]1[CH:33]=[C:32]([C:34](=[O:46])[C:35]2[CH:40]=[CH:39][CH:38]=[C:37]([C:41]([O:43][CH2:44][CH3:45])=[O:42])[CH:36]=2)[CH:31]=[CH:30][C:29]=1[O:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][C:7]1[CH:8]=[CH:9][C:4]([C:1](=[O:3])[CH3:2])=[CH:5][CH:6]=1)[CH3:23]