反应详情

106 mg of 5-(3-methylphenyl)isoxazole, 119 mg of N-bromosuccinimide and 2 mg of benzoyl peroxide were dissolved in 10 ml of carbon tetrachloride, and the solution was refluxed for 3 hours with stirring. After cooling, the precipitate was separated by filtration, and concentrated under reduced pressure to give 5-(3-bromomethylphenyl)isoxazole as a pale yellow oily product.

1. temperaturethe solution was refluxed for 3 hours
2. temperatureAfter cooling
3. customthe precipitate was separated by filtration
4. concentrationconcentrated under reduced pressure