3-(Thiophen-3-yl)benzaldehyde → HCID 19744695, compound

HRID 2254412Notes

Reaction equation

HRID 2254412 reaction equation
[CH3:1][C:2]([CH3:20])([CH3:19])[C:3]#[C:4]/[CH:5]=[CH:6]/[CH2:7][N:8]([CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([NH2:18])[CH:13]=1)[CH2:9][CH3:10].[S:21]1[CH:25]=[CH:24][C:23]([C:26]2[CH:27]=[C:28]([CH:31]=[CH:32][CH:33]=2)[CH:29]=O)=[CH:22]1.NC1C=C(C=CC=1)CN>>[CH3:20][C:2]([CH3:19])([CH3:1])[C:3]#[C:4]/[CH:5]=[CH:6]/[CH2:7][N:8]([CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([NH:18][CH2:29][C:28]2[CH:31]=[CH:32][CH:33]=[C:26]([C:23]3[CH:24]=[CH:25][S:21][CH:22]=3)[CH:27]=2)[CH:13]=1)[CH2:9][CH3:10]

Participants

4

Reactant 3

HCID 45475263-(Thiophen-3-yl)benzaldehydeHCID 46288313-AminobenzylamineHCID 19917001HCID 19917001, compound

Product 1

HCID 19744695HCID 19744695, compound

Procedure

Compounds of Examples 175 to 180 were obtained by performing the same reaction as in Example 174 except that instead of the starting compound (E)-N-(6,6-dimethyl-2-hepten-4-ynyl)-N-ethyl-3-aminobenzylamine and/or 3-(3-thienyl)benzaldehyde, the corresponding 3-aminobenzylamine derivatives and/or 3-substituted benzaldehyde derivatives were used.

Sources & evidence

ORD record
ord-853da33839544c5781528786745b7b8a
Source dataset
uspto-grants-1993_08
Patent number
US05234946

Reaction notes

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