3-Amino-2-methylbenzoic acid methyl ester → 2-Methyl-3-(1H-pyrrol-1-yl)benzenemethanol

HRID 2254462Notes

Reaction equation

HRID 2254462 reaction equation
[NH2:1][C:2]1[C:3]([CH3:12])=[C:4]([CH:9]=[CH:10][CH:11]=1)[C:5]([O:7]C)=O.N[C:14]1[CH:15]=C(C(C)=[CH:22][CH:23]=1)C(OC)=O>>[CH3:12][C:3]1[C:2]([N:1]2[CH:22]=[CH:23][CH:14]=[CH:15]2)=[CH:11][CH:10]=[CH:9][C:4]=1[CH2:5][OH:7]

Participants

3

Reactant 2

HCID 38010253-Amino-2-methylbenzoic acid methyl esterHCID 15049977Methyl 5-Amino-2-methylbenzoate

Product 1

HCID 155817552-Methyl-3-(1H-pyrrol-1-yl)benzenemethanol

Procedure

When the same reaction as in Referential Example 18 is carried out using methyl 3-amino-2-methylbenzoate instead of the starting methyl 3-amino-6-methylbenzoate, 2-methyl-3-(1-pyrrolyl)benzyl alcohol is obtained.

Workup

  1. customWhen the same reaction as in Referential Example 18

Sources & evidence

ORD record
ord-e168d1b0f37e4ac1aa4ea5a078633a35
Source dataset
uspto-grants-1993_08
Patent number
US05234946

Reaction notes

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