Sodium ethoxide → HCID 54042628, compound

Participants

Reaction Steps

1.21 g of the resulting phosphonium salt was dissolved in 45 ml of ethanol, and 0.35 g of 3-formylbenzyl alcohol and 0.27 g of sodium ethoxide were added. The mixture was stirred at room temperature for 2 hours. The solvent was evaporated under reduced pressure. The residue was distributed between ethyl acetate and water, worked up in a customary manner, and purified by silica gel column chromatography [Wakogel C-300, 100 g; eluting solvent: hexane/ethyl acetate=10/1→5/1] to give 0.34 g (yield 46%) of an E-form of 3-[2-[3-(3-thienyl)-phenyl]ethenyl]benzyl alcohol and 0.34 g of its Z-form.

Provenance & Evidence