HCID 54220456, compound → HCID 53979206, compound

HRID 2254466Notes

Reaction equation

HRID 2254466 reaction equation
N1(C2C=C(/C=C\C3C=C(C=CC=3)CO)C=CC=2)C=CC=C1.N1C=CC=C(C2C=C(/C=C\C3C=C(C=CC=3)CO)C=CC=2)C=1.[S:44]1[CH:48]=[CH:47][C:46]([C:49]2[CH:50]=[C:51](/[CH:55]=[CH:56]\[C:57]3[CH:58]=[C:59]([CH:62]=[CH:63][CH:64]=3)[CH2:60][OH:61])[CH:52]=[CH:53][CH:54]=2)=[CH:45]1.N1(C2C=C(CCC3C=C(C=CC=3)CO)C=CC=2)C=CC=C1.N1C=CC=C(C2C=C(CCC3C=C(C=CC=3)CO)C=CC=2)C=1>>[S:44]1[CH:48]=[CH:47][C:46]([C:49]2[CH:50]=[C:51]([CH2:55][CH2:56][C:57]3[CH:58]=[C:59]([CH:62]=[CH:63][CH:64]=3)[CH2:60][OH:61])[CH:52]=[CH:53][CH:54]=2)=[CH:45]1

Participants

6

Reactant 5

HCID 54220456HCID 54220456, compoundHCID 54476579HCID 54476579, compoundHCID 67855275HCID 67855275, compoundHCID 67855276HCID 67855276, compoundHCID 67855278HCID 67855278, compound

Product 1

HCID 53979206HCID 53979206, compound

Procedure

When the same reduction as in Referential Example 47 is carried out using (Z)-3-[2-[3-(1-pyrrolyl)phenyl]ethenyl]benzyl alcohol or (Z)-3-[2-[3-(3-pyridyl)phenyl]ethenyl]benzyl alcohol instead of the starting (Z)-3-[2-[3-(3-thienyl)phenyl]ethenyl]benzyl alcohol, 3-[2-[3-(1-pyrrolyl)phenyl]ethyl]benzyl alcohol and 3-[2-[3-(3-pyridyl)phenyl]ethyl]benzyl alcohol are obtained.

Workup

  1. customare obtained

Sources & evidence

ORD record
ord-00a8a7d4e4ff4c488cb6ad8957f34ee7
Source dataset
uspto-grants-1993_08
Patent number
US05234946

Reaction notes

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