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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2254477Generated: October 31, 2026

Potassium Carbonate → 3-[3-(5-Oxazolyl)phenylthiomethyl)benzyl alcohol

https://huagongshe.com/reaction/2254477

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
ReactantTosylmethyl isocyanideHCID 161915—
Reactant3-[3-(Hydroxymethyl)benzylthio]benzaldehydeHCID 19744644—
Product3-[3-(5-Oxazolyl)phenylthiomethyl)benzyl alcoholHCID 6785526684.3%

Reaction Steps

When the same reaction as in Referential Example 33 was carried out except using 172 mg of the resulting aldehyde compound, 130 mg of p-toluenesulfonylmethyl isocyanide and 92 mg of potassium carbonate, 167 mg (yield 84%) of the captioned compound wss obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05234946
Source datasetuspto-grants-1993_08
ORD IDord-08b49b6bc91e4c36b5bb81997b212b7e
Source noteuspto-grants-1993_08