HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannane, tributyl-3-thienyl- → 5-(3-Thienyl)-3-thiophenecarboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannane, tributyl-3-thienyl- | HCID 10959689 | — |
| Reactant | Ethyl 5-bromothiophene-3-carboxylate | HCID 15293216 | — |
| Catalyst | Tetrakis(triphenylphosphine)palladium | HCID 11979704 | — |
| Product | 5-(3-Thienyl)-3-thiophenecarboxylic acid ethyl ester | HCID 54574263 | 51% |
Reaction Steps
The same reaction as in Referential Example 37 was carried out except using 380 mg of 5-bromo-3-thiophenecarboxylic acid ethyl ester [see J. Am. Chem. Soc., 26, 2446 (1954)], 730 mg of tributyl(3-thienyl)stannane and 10 mg of tetrakis(triphenylphosphine) palladium to give 172 mg (yield 51%) of 5-(3-thienyl)-3-thiophenecarboxylic acid ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05234946 |
| Source dataset | uspto-grants-1993_08 |
| ORD ID | ord-2cf52f0aaa3747f5921658e97a0e6181 |
| Source note | uspto-grants-1993_08 |