Phosphorus pentachloride → HCID 178444339, compound

HRID 2254493Notes

Reaction equation

HRID 2254493 reaction equation
[CH2:1]([C@H:6]1[CH2:11][CH2:10][C@H:9]([C:12]2[CH:20]=[CH:19][C:15]([C:16](O)=[O:17])=[CH:14][CH:13]=2)[CH2:8][CH2:7]1)[CH2:2][CH2:3][CH2:4][CH3:5].P(Cl)(Cl)(Cl)(Cl)[Cl:22]>C1C=CC=CC=1>[CH2:1]([C@H:6]1[CH2:11][CH2:10][C@H:9]([C:12]2[CH:20]=[CH:19][C:15]([C:16]([Cl:22])=[O:17])=[CH:14][CH:13]=2)[CH2:8][CH2:7]1)[CH2:2][CH2:3][CH2:4][CH3:5]

Participants

4

Reactant 2

HCID 24819Phosphorus pentachlorideHCID 178444341HCID 178444341, compound

Product 1

HCID 178444339HCID 178444339, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

In a 30 ml-reaction vessel, 2.0 g (7.3 mM) of p-(trans-4-pentylcyclohexyl)benzoic acid and 10 ml of benzene were placed. To the mixture, 1.55 g (7.4 mM) of PCl5 was added in 25 minutes to room temperature, followed by heat-refluxing for 4 hours and distilling-off of the solvent to obtain p-(trans-4-pentylcyclohexyl)benzoic acid chloride.

Workup

  1. temperatureby heat-refluxing for 4 hours and distilling-off of the solvent

Sources & evidence

ORD record
ord-39ae0842fa134a50bfbf71c1b60dc71c
Source dataset
uspto-grants-1993_08
Patent number
US05236619

Reaction notes

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