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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2254576Generated: October 31, 2026

HCID 14842193, compound → HCID 136331494, compound

https://huagongshe.com/reaction/2254576

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 14842193HCID 14842193—
ReactantHCID 86747111HCID 86747111—
ProductHCID 136331494HCID 136331494—

Reaction Steps

The product of step (a) was reacted with bromomethyl compound (4) as described in Example 1 and the resulting diethyl N-(5-(N-((3,4-dihydro-4-oxo-3-((pivaloyl)oxy)methyl-6-quinazolinyl)methyl)prop-2-ynylamino)thien-2-oyl-L-glutamate hydrolysed, as described in Example 1 for the corresponding benzoyl analogue, to give CB 3866.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05236927
Source datasetuspto-grants-1993_08
ORD IDord-a39f2cbd00f944e19fb97e33dc1fb872
Source noteuspto-grants-1993_08