HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(Bromomethyl)-1-methylquinolin-2(1H)-one → HCID 20081976, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(Bromomethyl)-1-methylquinolin-2(1H)-one | HCID 15199065 | — |
| Reactant | HCID 20081948 | HCID 20081948 | — |
| Product | HCID 20081976 | HCID 20081976 | 46% |
Reaction Steps
Using the procedure described in Example 1, 6-bromomethyl-1,2-dihydro-1-methylquinolin-2-one was reacted with (2RS, 4RS)-4-(3-amino-5-hydroxyphenyl)-4-methoxy-2-methyltetrahydropyran to give (2RS, 4RS)-4-[3-(1,2-dihydro-1-methyl-2-oxoquinolin-6-ylmethylamino)-5-hydroxyphenyl]-4-methoxy-2-methyltetrahydropyran in 46% yield, as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05236919 |
| Source dataset | uspto-grants-1993_08 |
| ORD ID | ord-f30daf4bf31348eda3e62e5a3b0c48bd |
| Source note | uspto-grants-1993_08 |