HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → HCID 15679150, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Thiophenol | HCID 7969 | — |
| Reactant | HCID 12951792 | HCID 12951792 | — |
| Reactant | Ethyl acetate hexane | HCID 21226206 | — |
| Solvent | Triethanolamine | HCID 7618 | — |
| Product | HCID 15679150 | HCID 15679150 | — |
Reaction Steps
Analogously to Example 6(a), 200 mg of 17β-hydroxy-17α-methyl-6-methyleneandrost-4-en-3-one (Tetrahedron 20: 597, 1964) is reacted with thiophenol and formaldehyde in triethanolamine. After chromatography of the crude product on silica gel with a hexane-ethyl acetate gradient, 190 mg of 17β-hydroxy-17α-methyl-6-methylene-4-(phenylthiomethyl)androst-4-en-3-one is obtained as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05236912 |
| Source dataset | uspto-grants-1993_08 |
| ORD ID | ord-64beff46361e4cd7b3e6a6be5235a83e |
| Source note | uspto-grants-1993_08 |