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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2254640Generated: November 1, 2026

Bromine → 6-(2,2,2-Trifluoroethoxy)-1,3-benzothiazol-2-amine

https://huagongshe.com/reaction/2254640

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromineHCID 24408—
ReactantPotassium thiocyanateHCID 516872—
Reactant4-(2,2,2-Trifluoroethoxy)anilineHCID 2777119—
SolventAcetic AcidHCID 176—
Product6-(2,2,2-Trifluoroethoxy)-1,3-benzothiazol-2-amineHCID 10562485—

Reaction Steps

The procedure is as in Example 1, starting with 4-(2,2,2-trifluoroethoxy)aniline, potassium thiocyanate and bromine in acetic acid, to obtain 6-(2,2,2-trifluoroethoxy)-2-benzothiazolamine, m.p. 134° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05236940
Source datasetuspto-grants-1993_08
ORD IDord-c635d7700aa4455ab4b9578596b8f712
Source noteuspto-grants-1993_08