HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Hydroxyacetamidine → N'-[(3,4-dimethoxy-5-nitrobenzoyl)oxy]acetamidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Hydroxyacetamidine | HCID 30926 | — |
| Reactant | 1-(3,4-Dimethoxy-5-nitrobenzoyl)imidazole | HCID 21459020 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N'-[(3,4-dimethoxy-5-nitrobenzoyl)oxy]acetamidine | HCID 53789064 | — |
Reaction Steps
10.0 g of 1-(3,4-dimethoxy-5-nitrobenzoyl)imidazole in 50 ml of dimethylformamide are treated with 6.95 g of acetamidoxime, whereupon the mixture is stirred at 70° for 1 hour. After cooling, the mixture is poured into 500 ml of ice-water and stirred for 30 minutes. The separated crystals are filtered under suction and washed with water. After crystallization from ethyl acetate there is obtained N'-[(3,4-dimethoxy-5-nitrobenzoyl)oxy]acetamidine in the form of colorless crystals of m.p. 165°-166°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05236952 |
| Source dataset | uspto-grants-1993_08 |
| ORD ID | ord-8c7bb166f29b4318b26b8fefa8fb7a9f |
| Source note | uspto-grants-1993_08 |